This website is intended for US residents.

Proven Protection

Proven Protection

AKYNZEO works to prevent nausea and vomiting from highly and moderately emetogenic chemo medicines, including some medicines that are used in the treatment of breast and lung cancer.

AKYNZEO is effective for people who are at risk for vomiting that happens right away (acute) or later (delayed).

In a clinical study involving 135 patients who were taking cisplatin-based chemotherapy, AKYNZEO was compared against palonosetron, a different antiemetic treatment:

90%
of patients who received AKYNZEO had no vomiting for as long as 5 days after chemo.

99%
of patients who received AKYNZEO had no vomiting within 24 hours of chemo.

AKYNZEO has also prevented nausea and vomiting for people who have had several cycles of chemo.

In this clinical study, the most common side effects of stomach upset, fatigue, constipation, and skin redness occurred in fewer than 4% of patients.

In clinical studies, AKYNZEO patients experienced no vomiting for as long as 5 days after chemo.

Approved Use/Important Safety Considerations

AKYNZEO is a prescription medicine called an “antiemetic.” AKYNZEO is used in people to help prevent the nausea and vomiting that happens right away or later with certain anti-cancer medicines (chemotherapy).

It is not known if AKYNZEO is safe and effective in children under 18 years of age.

Important Safety Considerations

  • AKYNZEO may cause serious allergic reactions, such as anaphylaxis. Get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction to AKYNZEO: hives, swollen face, trouble breathing, or chest pain
  • Serotonin syndrome can happen with AKYNZEO particularly with certain other medicines such as anti‑depressants and anti‑migraine medicines and can be life‑threatening. Go to the nearest hospital emergency room right away if you get any of the following symptoms: agitation, hallucinations or other changes in mental status, dizziness, muscle twitching, or seizures
  • The most common side effects of AKYNZEO are headache, weakness, fatigue, upset stomach, constipation, and skin redness

For more about AKYNZEO, talk to your doctor or see the Full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Expand

Approved Use/Important Safety Considerations

AKYNZEO is a prescription medicine called an “antiemetic.” AKYNZEO is used in people to help prevent the nausea and vomiting that happens right away or later with certain anti-cancer medicines (chemotherapy).

It is not known if AKYNZEO is safe and effective in children under 18 years of age.

Important Safety Considerations

  • AKYNZEO may cause serious allergic reactions, such as anaphylaxis. Get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction to AKYNZEO: hives, swollen face, trouble breathing, or chest pain
  • Serotonin syndrome can happen with AKYNZEO particularly with certain other medicines such as anti‑depressants and anti‑migraine medicines and can be life‑threatening. Go to the nearest hospital emergency room right away if you get any of the following symptoms: agitation, hallucinations or other changes in mental status, dizziness, muscle twitching, or seizures
  • The most common side effects of AKYNZEO are headache, weakness, fatigue, upset stomach, constipation, and skin redness

For more about AKYNZEO, talk to your doctor or see the Full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.